One of our US distributors, HypOxygen, are soon to be exhibiting at the American Association for Cancer Research event “Function of Tumor Microenvironment in Cancer Progression” in San Diego, California between the 7th and 10th of January. At the meeting HypOxygen will be on hand to discuss how working within the hypoxic microenvironment provided by a Whitley Hypoxystation is greatly beneficial to this area of work. The statement from HypOxygen below expresses this.
The hypoxic microenvironment is a characteristic feature of many solid tumors, and the very low level of oxygenation there dramatically influences the Hallmarks of Cancer from reprogramming energy metabolism through sustained angiogenesis to evasion of the immune response. And as our Hypoxystation users are showing, research into signaling pathways, cancer progression, and therapy resistance consistently benefits from the use of a closed hypoxia workstation for physiological cell culture. The Hypoxystation creates conditions that mimic the cellular microenvironment with regard to oxygen tension, temperature, and humidity.
To see what our users are doing in “Hypoxia Applications in Cancer Research” click here. Also, Violaine See of the University of Liverpool describes her work using the Hypoxystation in “Cellular memory of hypoxia elicits neuroblastoma metastasis and enables invasion by non-aggressive neighbouring cells”, published in Oncogenesis 4 (2015), which you can find on the DWS website here. Ayse Latif, University of Manchester, has carried out metabolism studies of gynecological cancer cells with the Seahorse XFe Analyzer; have a look here.
HypOxygen hope to see you at the AACR “Function of Tumor Microenvironment in Cancer Progression” meeting in San Diego between 7-10 January. HypOxygen will be showing the Hypoxystation for low oxygen cell culture and would love to tell you more about its benefits.