Uncovering the Effects of Hypoxia in CNS Disorders Using Whitley Workstations

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Uncovering the Effects of Hypoxia in CNS Disorders Using Whitley Workstations

Dr Scott Allen (pictured above) is a Lecturer in Neuroscience at the Sheffield Institute for Translational Neuroscience (SITraN). Part of the University of Sheffield, SITraN is one of the world leading centres for research into Motor Neurone Disease, Alzheimer’s and Parkinson’s Disease.

We recently spoke to Dr Allen about his research, which focuses on how hypoxia (low oxygen) affects the metabolism of people with neurological disorders. Dr Allen remarked that historically it has been difficult to measure metabolism under hypoxic conditions due to the lack of available technology. Now, with the Whitley H35 HEPA Hypoxystation, it is possible to expose astrocytes (brain cells) to different levels of hypoxia and then asses how the metabolic profile of the cells has altered using a Seahorse Analyzer housed inside a Whitley i2 Instrument Workstation.    Scott Allen working

“Scientific advancement goes hand-in-hand with technological advancement; now we have this ability to measure and assess how hypoxia affects the metabolic profile of neurological diseases… we can hopefully improve the quality of life for people with Alzheimer’s and Motor Neurone Disease, and also extend their lives as well.”  

 To learn more about Dr Allen’s research: 

Watch this video


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